Understanding Alzheimer's disease in diverse populations
HABS-HD - Project 1
This study is looking at how Alzheimer's disease affects different people, especially African Americans, to better understand the signs of the disease and how they change over time, so we can improve treatments for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of North Texas Hlth Sci Ctr NIH-funded |
| Lab location | 1 site (Fort Worth, United States) |
| Project ID | NIH-10916346 on NIH RePORTER |
What this research studies
This research investigates the biological framework of Alzheimer's disease (AD) and its relevance to diverse populations, particularly focusing on African Americans who are disproportionately affected by AD and related dementias. The study aims to analyze the impact of various factors on the biomarkers of AD throughout adulthood, using a community-based approach to gather data. By including a diverse participant pool, the research seeks to enhance the understanding of how these biomarkers manifest and progress in different racial groups, which has been largely overlooked in previous studies. The findings could inform future clinical trials and therapeutic strategies tailored to these populations.
Who could benefit from this research
Good fit: Ideal candidates for participation include African American adults aged 21 and older who are at risk for or diagnosed with Alzheimer's disease or related dementias.
Not a fit: Patients who are not African American or do not fall within the age range of 21 and older may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and inclusive treatments for Alzheimer's disease that consider the unique experiences and biological factors of diverse populations.
How similar studies have performed: While there has been significant research on Alzheimer's disease, this study's focus on diverse populations and the application of the AT(N) framework is relatively novel and aims to fill a critical gap in existing literature.
Where this research is happening
Fort Worth, United States
- University of North Texas Hlth Sci Ctr — Fort Worth, United States (Active)
Researchers
- Principal investigator: O'bryant, Sid E — University of North Texas Hlth Sci Ctr
- Study coordinator: O'bryant, Sid E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.