NIH-funded research R01 grant

Understanding Alzheimer's disease in African Americans

Official title: Innovative Deep Phenotyping of African Americans at Risk for Alzheimers disease

Funded at University of Miami School of Medicine · NIH-11041129 · Data updated 2026-11-12

This study is all about helping African American older adults by finding better ways to detect Alzheimer's disease early, using special tests that fit their health needs, and making it easy for them to participate from home or with transportation for important scans.

More Alzheimer's Disease research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Miami School of Medicine
NIH-funded
Lab location1 site (Coral Gables, United States)
Project startJune 1, 2023
Project endFebruary 29, 2028
Funding year2025
Award (this year)$1,541,121
NIH project number5R01AG077677-03
Project IDNIH-11041129 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are African American older adults who are at risk for Alzheimer's disease or related disorders.

Less likely to help

Patients who are not African American or those who do not have a risk for Alzheimer's disease may not benefit from this research.

What this research studies

This research focuses on improving the understanding and early detection of Alzheimer's disease and related disorders specifically in African American older adults. It aims to address the significant under-representation of this population in clinical research by employing innovative cognitive and biomarker assessments tailored to their unique health profiles. The study will utilize home-based assessments and provide transportation for necessary imaging studies, making participation more accessible. By deeply phenotyping African Americans, the research seeks to enhance the diagnostic and prognostic capabilities of biomarkers associated with Alzheimer's disease.

Why it matters

Potential benefit: If successful, this research could lead to better early detection and tailored therapeutic approaches for Alzheimer's disease in African American populations.

How similar studies have gone: Other research has shown success in using home-based assessments and culturally tailored approaches to engage diverse populations in Alzheimer's research.

Where this research is happening

  • University of Miami School of Medicine
    Coral Gables, United States
    Active

Researchers

  • Principal investigator: Loewenstein, David — University of Miami School of Medicine
  • Study coordinator: Loewenstein, David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.