Understanding Alzheimer's disease and related dementias through community-based research.
Core B: University of Kentucky Alzheimer's Disease Core Center
This study is looking at a group of people over time to learn more about normal aging and the early signs of Alzheimer's and related dementias, and it involves a brain autopsy after death to help researchers connect symptoms with what they find in the brain, all with the goal of improving how we diagnose and treat dementia.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10880727 on NIH RePORTER |
What this research studies
This research focuses on a well-characterized group of individuals from the community who are being followed over time to understand normal aging and the early stages of Alzheimer's disease and related dementias. Participants are required to undergo brain autopsy after death, which helps researchers correlate clinical symptoms with pathological findings. The study aims to identify early signs of dementia and the various factors that contribute to its development, including genetic and biomarker analysis. By examining a diverse cohort, the research seeks to improve diagnosis and treatment strategies for dementia.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly individuals who are at high risk for developing dementia or are experiencing early signs of cognitive decline.
Not a fit: Patients who are not elderly or do not have any signs of cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better management of Alzheimer's disease and related dementias.
How similar studies have performed: Previous research has shown success in understanding dementia through longitudinal studies and autopsy findings, making this approach both validated and promising.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Jicha, Gregory a — University of Kentucky
- Study coordinator: Jicha, Gregory a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.