Understanding Alzheimer's Disease and Related Dementias at the University of Kentucky

Core B: University of Kentucky Alzheimer's Disease Core Center

NIH-funded research University of Kentucky · NIH-11123376

This effort helps us learn more about how Alzheimer's disease and other memory conditions develop in older adults by carefully observing them over time.

Quick facts

Grant typeP30 center grant
Study typeNIH-funded research
Funding institutionUniversity of Kentucky NIH-funded
Lab location1 site (Lexington, United States)
Project IDNIH-11123376 on NIH RePORTER

What this research studies

We are building a comprehensive group of community members, including those with normal aging and those showing early signs of memory changes, to follow their health journey. This involves collecting detailed information about their health, genetics, and biological markers, and for most, conducting a brain autopsy after death. This approach helps us understand the many different types of dementia and how they progress, especially the complex ways multiple conditions can affect memory later in life. Our goal is to better define the early stages of these diseases and improve future diagnosis and care.

Who could benefit from this research

Good fit: Ideal participants are older adults from the community, including those with normal memory and those experiencing early memory changes, who are willing to participate in long-term follow-up and contribute to brain autopsy studies.

Not a fit: Patients not interested in long-term observation or contributing to post-mortem brain studies may not find direct benefit from participating in this specific research core.

Why it matters

Potential benefit: If successful, this work could lead to a much clearer understanding of how different types of dementia develop, which may help doctors diagnose conditions earlier and develop more targeted treatments.

How similar studies have performed: Similar long-term cohort studies have made significant contributions to our understanding of dementia, and this center has already made major advancements in recognizing the diverse causes of memory loss.

Where this research is happening

Lexington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's DiseaseAlzheimer's Disease Core CenterAlzheimer's disease and related dementia
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.