Understanding Alzheimer's disease and related dementias
Official title: Core B: Clinical Core
Funded at University of Pennsylvania · NIH-10935306 · Data updated 2026-11-12
This study is looking at how Alzheimer's and similar types of dementia affect people differently, and it's for anyone with these conditions to help find ways to slow down memory loss and improve their quality of life.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 15, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $527,191 |
| NIH project number | 1P01AG084497-01A1 |
| Project ID | NIH-10935306 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias, particularly those with varying symptoms and progression rates.
✕Less likely to help
Patients with non-dementia related cognitive impairments or those without a diagnosis of Alzheimer's disease or related dementias may not benefit from this research.
What this research studies
This research focuses on Alzheimer's disease and related dementias, aiming to understand the varying clinical trajectories and cognitive decline associated with these conditions. The Clinical Core at the University of Pennsylvania will recruit and assess patients to gather human data, which will help identify the mechanisms behind the differences in disease progression. By studying patients with different types of dementia, including Lewy body disorders, the research seeks to uncover why some individuals experience rapid cognitive decline while others do not. The ultimate goal is to develop interventions that can prevent or slow down cognitive decline in affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing cognitive decline in patients with Alzheimer's disease and related dementias.
How similar studies have gone: Previous research has shown promise in understanding the mechanisms of Alzheimer's disease and related dementias, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Weintraub, Daniel — University of Pennsylvania
- Study coordinator: Weintraub, Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.