Understanding Alzheimer's Disease and related dementias
Official title: Core A: Administrative Core
Funded at University of Pennsylvania · NIH-10935305 · Data updated 2026-11-12
This study is looking into why some people with Alzheimer's and similar conditions, especially those with Lewy body disorders, experience memory loss sooner than others, and it's for anyone interested in finding new treatments to help improve their lives.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 15, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $124,985 |
| NIH project number | 1P01AG084497-01A1 |
| Project ID | NIH-10935305 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's Disease, Lewy body disorders, or related dementias.
✕Less likely to help
Patients with non-neurodegenerative cognitive impairments may not receive benefit from this research.
What this research studies
This research focuses on understanding the mechanisms behind Alzheimer's Disease and related dementias, particularly in patients with Lewy body disorders. The Administrative Core at the University of Pennsylvania coordinates various projects aimed at exploring why some individuals experience cognitive decline earlier than others. By utilizing human-derived materials, including brain tissue and biofluids, the research aims to derive insights that could lead to new therapies. The core also emphasizes collaboration and communication among researchers and advocates to enhance the impact of their findings.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve the quality of life for patients with Alzheimer's Disease and related dementias.
How similar studies have gone: Previous research has shown promise in understanding the mechanisms of Alzheimer's Disease, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Chen-Plotkin, Alice S — University of Pennsylvania
- Study coordinator: Chen-Plotkin, Alice S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.