Understanding Alzheimer's disease and related dementias
Clinical Core
This study is looking at how Alzheimer's disease and similar conditions affect older adults, and it invites people with Mild Cognitive Impairment or different types of dementia to join in so we can learn more about their experiences and health over time.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10916431 on NIH RePORTER |
What this research studies
This research focuses on exploring the different clinical and pathological characteristics of Alzheimer's disease and related dementias. It involves enrolling and monitoring a diverse group of older individuals, including those with Mild Cognitive Impairment and various forms of dementia, to gather valuable insights. The study aims to enhance understanding of these conditions through extensive data collection and collaboration with other research cores. Participants will be followed over time to track changes and outcomes related to their cognitive health.
Who could benefit from this research
Good fit: Ideal candidates include older individuals with Mild Cognitive Impairment, various types of dementia, or those who are cognitively normal but carry the APOE e4 allele.
Not a fit: Patients with early-stage Alzheimer's disease or those without any cognitive impairment may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for Alzheimer's disease and related dementias.
How similar studies have performed: Previous research has shown success in understanding Alzheimer's disease through similar longitudinal studies, indicating a promising approach.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Appleby, Brian Stephen — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Appleby, Brian Stephen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.