Understanding Alzheimer's and Related Dementias Through Genetic Information
Genome Center for Alzheimer's Disease (GCAD)
This project collects and organizes genetic information from many people to better understand Alzheimer's disease and related memory conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11180068 on NIH RePORTER |
What this research studies
Alzheimer's disease and related dementias affect millions, and we urgently need new ways to prevent and treat them. This project gathers and processes vast amounts of genetic and biological data from individuals with these conditions and healthy controls. By carefully organizing and analyzing this information, we hope to uncover new genetic clues that point to the causes of these diseases. This deeper understanding could lead to the discovery of new targets for future medicines and treatments.
Who could benefit from this research
Good fit: This project primarily uses existing genetic data from individuals with Alzheimer's disease, frontotemporal dementias, Lewy body dementia, and other related conditions, as well as cognitively normal elderly controls.
Not a fit: Patients not diagnosed with Alzheimer's disease or related dementias, or those not contributing genetic data to the Alzheimer's Disease Sequencing Project, would not directly benefit from this specific data analysis.
Why it matters
Potential benefit: If successful, this work could identify new genetic factors that contribute to Alzheimer's and related dementias, paving the way for new diagnostic tools and treatments.
How similar studies have performed: This project builds upon the successful collection of genetic data by the Alzheimer's Disease Sequencing Project, expanding the types of data analyzed and the scope of conditions covered.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Schellenberg, Gerard David — University of Pennsylvania
- Study coordinator: Schellenberg, Gerard David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.