Understanding alcohol use after weight loss surgery

Biobehavioral Mechanistic Model of Alcohol Use Following Bariatric Surgery: The BREW ME Model

NIH-funded research Sanford Research North · NIH-10774539

This study looks at how weight loss surgery might change drinking habits and the risk of alcohol problems, focusing on how the gut and brain work together after surgery, so we can better understand what might lead some patients to drink more afterward.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSanford Research North NIH-funded
Lab location1 site (Fargo, United States)
Project IDNIH-10774539 on NIH RePORTER

What this research studies

This research investigates how bariatric surgery affects alcohol consumption and the risk of developing alcohol use disorder. It focuses on the role of the gut microbiome and its interaction with the brain in influencing drinking behaviors post-surgery. By examining these mechanisms, the study aims to identify factors that contribute to increased alcohol use in patients who have undergone metabolic and bariatric surgery. The research employs a transdisciplinary approach, integrating insights from microbiology, neuroscience, and behavioral science.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have undergone or are considering metabolic and bariatric surgery and are concerned about alcohol use.

Not a fit: Patients who have not undergone bariatric surgery or do not have concerns about alcohol use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing alcohol use disorder in patients after bariatric surgery.

How similar studies have performed: While the specific mechanisms of alcohol use post-bariatric surgery are still being explored, there is growing evidence supporting the role of the microbiome in influencing alcohol consumption behaviors.

Where this research is happening

Fargo, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.