Understanding Alcohol-Associated Liver Conditions After a Sudden Worsening
Defining Phenotypes of Alcohol-Associated Liver Disease with Acute Hepatic Decompensation
This project aims to better understand how alcohol-associated liver conditions progress in patients who experience a sudden worsening of their liver health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11100009 on NIH RePORTER |
What this research studies
We are creating a registry and collecting samples from patients with alcohol-associated liver conditions who are hospitalized due to a sudden decline in liver function. Our goal is to follow these patients for two years after they leave the hospital, looking at their alcohol use, blood tests, imaging results, nutrition, and overall physical health. By gathering this information, we hope to identify different ways the condition can progress and develop a tool to predict who might recover well.
Who could benefit from this research
Good fit: Ideal candidates are patients with alcohol-associated liver conditions and alcohol use disorder who are currently hospitalized with acute hepatic decompensation.
Not a fit: Patients who do not have alcohol-associated liver conditions or who are not experiencing acute hepatic decompensation would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to better predictions of recovery for patients with alcohol-associated liver conditions and help tailor future treatments.
How similar studies have performed: While the natural history of alcohol-associated liver conditions is complex, this project takes a novel, multifaceted approach to identify distinct trajectories and develop patient-specific risk prediction models.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Kwong, Allison — Stanford University
- Study coordinator: Kwong, Allison
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.