Understanding aging and chronic diseases through cell analysis
Biospecimen-Core
['FUNDING_OTHER'] · UNIVERSITY OF MINNESOTA · NIH-10899782
This study is looking at how old cells in our bodies might affect our health as we age, and it’s for anyone interested in how we can improve health and treat diseases in older adults by exploring new drugs that can help get rid of these old cells.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10899782 on ClinicalTrials.gov |
What this research studies
This research investigates the role of senescent cells, which accumulate with age and contribute to various chronic diseases. By analyzing specific tissues such as adipose, skeletal muscle, liver, and ovarian tissues, the study aims to understand how these cells affect healthy aging and disease progression. The research involves collecting and characterizing biological samples from healthy individuals to explore the potential of senolytic drugs that eliminate these cells. This could lead to advancements in treatments that improve health outcomes for aging populations.
Who could benefit from this research
Good fit: Ideal candidates for participation are healthy individuals of various ages who are interested in contributing to research on aging and chronic diseases.
Not a fit: Patients with acute illnesses or those who are not in a stable health condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance healthy aging and reduce the impact of age-related diseases.
How similar studies have performed: Previous research has shown promising results with senolytic drugs in animal models, indicating potential for success in human applications.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: IKRAMUDDIN, SAYEED — UNIVERSITY OF MINNESOTA
- Study coordinator: IKRAMUDDIN, SAYEED
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.