Understanding Aggression in the Brain

Sex Differences in Neural Circuit Mechanisms of Aggression

['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11140982

This research aims to uncover how brain circuits contribute to aggressive behaviors, hoping to find new ways to help people struggling with aggression.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11140982 on ClinicalTrials.gov

What this research studies

Aggression is a natural part of social life, but it can become harmful and lead to serious problems for individuals and society. Currently, we have very few effective treatments because we don't fully understand what happens in the brain to cause aggression. This project uses advanced brain imaging techniques to map out which brain areas are active during aggressive and non-aggressive interactions. By looking at how these brain regions connect and communicate, we hope to identify new targets for future therapies.

Who could benefit from this research

Good fit: This foundational research is not directly recruiting patients but aims to benefit individuals who experience problematic aggressive behaviors.

Not a fit: Patients seeking immediate treatment or direct clinical intervention will not find direct benefit from this basic science project.

Why it matters

Potential benefit: If successful, this work could lead to a deeper understanding of aggression, paving the way for the development of new and more effective treatments for those affected.

How similar studies have performed: This project uses novel computational and imaging approaches to explore brain mechanisms of aggression, building on a limited existing understanding.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.