Understanding age-related hearing loss using mouse models
Official title: Animal, Behavior and Tissue Core
Funded at University of Arizona · NIH-10910234 · Data updated 2026-11-12
This study is looking at how genes might affect hearing loss as we get older by using special mice, and it aims to help us understand what happens in our ears as we age, which could lead to better solutions for older adults experiencing hearing loss.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $398,480 |
| NIH project number | 7P01AG051443-07 |
| Project ID | NIH-10910234 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing hearing loss or those at risk of developing age-related hearing impairments.
✕Less likely to help
Patients with hearing loss due to non-age-related factors, such as noise exposure or infections, may not benefit from this research.
What this research studies
This research focuses on developing and utilizing aged and genetically engineered mouse models to investigate the genetic factors contributing to age-related hearing loss (ARHL). By breeding and maintaining specific strains of aged mice, the research aims to explore the structural and functional changes in the auditory system as it ages. The project will employ various genetic techniques to analyze how these changes affect hearing capabilities. The findings could provide insights into the biological mechanisms behind hearing loss in older adults.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating age-related hearing loss in humans.
How similar studies have gone: Previous research using similar mouse models has shown promise in understanding the genetic basis of hearing loss, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Yamoah, Ebenezer N — University of Arizona
- Study coordinator: Yamoah, Ebenezer N
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.