Understanding Acute Kidney Injury with Tissue Samples
AKI Matched Phenotype Linked Evaluation with Tissue (AMPLE-Tissue)
['FUNDING_U01'] · JOHNS HOPKINS UNIVERSITY · NIH-11173862
This project collects kidney tissue and blood samples from hospitalized patients with acute kidney injury to better understand this condition and find new ways to treat it.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11173862 on ClinicalTrials.gov |
What this research studies
Acute kidney injury (AKI) is a common and serious condition, but we don't yet have specific treatments because it affects people differently. This project is part of a larger national effort called the Kidney Precision Medicine Program (KPMP) that aims to change this. We are carefully collecting small tissue samples from the kidney, along with blood samples, from patients who are hospitalized with AKI. By studying these samples, we hope to uncover the exact causes of AKI and identify new targets for future medicines.
Who could benefit from this research
Good fit: Ideal candidates are hospitalized patients experiencing acute kidney injury who are willing to provide kidney tissue and blood samples.
Not a fit: Patients who do not have acute kidney injury or are not hospitalized for this condition would not directly benefit from participating in this specific research.
Why it matters
Potential benefit: If successful, this work could lead to the discovery of new ways to treat acute kidney injury, offering hope for better outcomes for patients.
How similar studies have performed: This project builds upon a successful first phase of the Kidney Precision Medicine Program, which has already safely enrolled many participants and collected valuable samples.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PARIKH, CHIRAG R — JOHNS HOPKINS UNIVERSITY
- Study coordinator: PARIKH, CHIRAG R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.