Understanding a Protein's Role in Healthy Aging
Competing Renewal P01
This research explores how a protein called FGF21 might help control aging and related health problems in older adults.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11141090 on NIH RePORTER |
What this research studies
As we age, inflammation and fat buildup in our organs can lead to chronic diseases. This project brings together experts to understand how our nervous system, metabolism, and immune system work together to influence aging. We are particularly interested in a protein called FGF21, which we believe plays a key role in controlling these aging processes. Our goal is to develop new medications that can boost FGF21's effects, potentially extending a healthy lifespan.
Who could benefit from this research
Good fit: This research is relevant for adults, particularly those over 21 years old, interested in the biological processes of aging and age-related health conditions.
Not a fit: Patients seeking immediate treatment for existing conditions may not directly benefit from this foundational research, which is focused on understanding aging mechanisms and developing future therapies.
Why it matters
Potential benefit: If successful, this work could lead to new medications that help slow down the aging process and prevent age-related diseases, improving overall health in older adults.
How similar studies have performed: This project builds upon new findings that FGF21 controls aspects of aging, moving towards pre-clinical development of FGF21-based therapies.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Dixit, Vishwa Deep — Yale University
- Study coordinator: Dixit, Vishwa Deep
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.