Understanding a protein that helps tuberculosis bacteria survive
A novel protein export chaperone of Mycobacterium tuberculosis
This study is looking at a special protein in the tuberculosis bacteria that helps it grow and cause illness, with the goal of finding new ways to treat TB and help patients feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project ID | NIH-11001046 on NIH RePORTER |
What this research studies
This research investigates a specific protein export chaperone called SatS in Mycobacterium tuberculosis, the bacteria responsible for tuberculosis. By exploring how SatS functions in exporting proteins critical for the bacteria's growth and virulence, the research aims to uncover new strategies to combat tuberculosis. The study will involve detailed analysis of SatS's mechanisms, its structure, and the proteins it interacts with, which could lead to innovative treatments for TB. Patients may benefit from this research as it could lead to the development of new anti-TB therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with tuberculosis or those at high risk of TB infection.
Not a fit: Patients with non-tuberculosis related infections or conditions will likely not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that more effectively combat tuberculosis.
How similar studies have performed: While the specific approach of targeting the SatS protein is novel, similar research has shown promise in understanding bacterial mechanisms and developing new treatments.
Where this research is happening
Fort Collins, United States
- Colorado State University — Fort Collins, United States (Active)
Researchers
- Principal investigator: Braunstein, Miriam S. — Colorado State University
- Study coordinator: Braunstein, Miriam S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.