Understanding a protein that helps control brain development
A Conserved RNA Binding Protein Required for Control of Key Developmental Pathways
['FUNDING_R01'] · EMORY UNIVERSITY · NIH-11019724
This study is looking at a protein called ZC3H14 to see how it helps the nervous system develop, which could give us clues about brain function and memory, and might help us understand certain brain disorders better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11019724 on ClinicalTrials.gov |
What this research studies
This research investigates the role of a specific RNA binding protein, ZC3H14, in the development of the nervous system. By studying this protein in various model organisms, including fruit flies, the research aims to uncover how it influences critical processes such as brain axon guidance and memory. The project focuses on understanding the molecular mechanisms by which ZC3H14 affects RNA regulation in neurons, which is essential for proper brain function and development. Insights gained from this research could lead to a better understanding of neurodevelopmental diseases linked to this protein.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurodevelopmental disorders or those interested in the genetic factors affecting brain development.
Not a fit: Patients with neurodevelopmental disorders not linked to RNA binding protein dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating neurodevelopmental disorders associated with RNA binding protein dysfunction.
How similar studies have performed: Previous research has shown success in understanding the roles of RNA binding proteins in developmental processes, indicating that this approach is promising.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MOBERG, KENNETH H — EMORY UNIVERSITY
- Study coordinator: MOBERG, KENNETH H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.