Understanding a New Heated Tobacco Product (IQOS) as a Way to Replace Menthol Cigarettes

The Abuse Liability of a Novel Heated Tobacco Product (IQOS) and Its Feasibility as a Menthol Cigarette Substitute.

NIH-funded research Virginia Commonwealth University · NIH-11109535

This project looks at whether a heated tobacco product called IQOS could help adult menthol cigarette smokers switch away from traditional cigarettes.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University NIH-funded
Lab location1 site (Richmond, United States)
Project IDNIH-11109535 on NIH RePORTER

What this research studies

We want to understand if a proposed ban on menthol cigarettes would encourage smokers to switch to less harmful options like heated tobacco products (HTPs). This project focuses on IQOS, an HTP authorized by the FDA, to see if its different flavors can help adult menthol smokers reduce their cigarette use. We will compare how addictive IQOS is compared to menthol cigarettes by looking at nicotine levels in the blood and how people use the products. This information will help determine if IQOS can truly serve as a substitute for menthol cigarettes.

Who could benefit from this research

Good fit: Ideal candidates for this work are adult menthol cigarette smokers who are at least 21 years old.

Not a fit: Individuals who do not smoke menthol cigarettes or are not interested in switching to heated tobacco products would not directly benefit from this particular research.

Why it matters

Potential benefit: If successful, this work could help menthol cigarette smokers find a potentially less harmful alternative, contributing to better public health outcomes.

How similar studies have performed: Validated clinical laboratory methods exist for comparing tobacco product abuse liability, and naturalistic assessments can confirm these findings.

Where this research is happening

Richmond, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.