NIH-funded research U01 cooperative agreement

UNC Food Allergy Program

Official title: UNC Food Allergy Initiative

Funded at Univ of North Carolina Chapel Hill · NIH-11284055 · Data updated 2026-11-12

This project will run clinical trials testing new treatments to help children and adults with food allergies.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startMarch 13, 2024
Project endFebruary 28, 2031
Funding year2026
Award (this year)$390,000
NIH project number5U01AI182033-03
Project IDNIH-11284055 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are people (children and adults) with diagnosed food allergies who meet the study criteria and can attend visits at UNC or participating CoFAR sites.

Less likely to help

People without confirmed food allergies, those unable to travel to study locations, or those with exclusionary medical conditions may not be eligible or likely to benefit.

What this research studies

At UNC you would join a network of clinics (CoFAR) running multi-center, randomized, placebo-controlled trials and smaller center-specific projects. Participants are randomly assigned to receive an active treatment or a placebo and will have scheduled clinic visits, allergy tests, and sample collection to track symptoms and safety. The center also trains junior investigators and builds research capacity to start and run future trials that may benefit people with food allergy.

Why it matters

Potential benefit: If successful, this work could lead to safer and more effective treatments and improved care for people with food allergies.

How similar studies have gone: Previous CoFAR and other food allergy clinical trials (including immunotherapy approaches) have shown promising results, though more research is needed to expand and refine treatments.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Kim, Edwin — Univ of North Carolina Chapel Hill
  • Study coordinator: Kim, Edwin

Related research

Other NIH-funded projects on the same topics.

  • New Horizons in preventing and treating food allergy

    A Johns Hopkins-led effort aims to advance how we prevent and treat food allergies across all ages by coordinating high-quality studies and developing better therapies.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11600582

  • New Horizons in Food Allergy Prevention and Treatment

    A large, multi-site program at Johns Hopkins aims to advance prevention and treatment of food allergies across all ages.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11580809

  • Food allergy outcomes by race/ethnicity from infancy through adolescence

    This study follows children with food allergies over time to understand how race and ethnicity relate to allergy management, outcomes, and quality of life.

    NIH research Northwestern University · Chicago, United States · NIH-11579222

  • Gut-brain links in food allergy responses

    A research grant is exploring how signals between the gut and brain drive dangerous reactions to foods, with the goal of helping people with food allergies.

    NIH research Yale University · New Haven, United States · NIH-11551492

  • Targeting gut microbes to restore food-tolerance in adults

    Aims to understand how gut bacteria and the lining of the gut interact to keep people with food allergies tolerant to what they eat.

    NIH research Boston Children's Hospital · Boston, United States · NIH-11551491

  • Environment and early-life exposures shaping food allergy in children

    This grant looks at how a child’s first year and their home environment may influence whether they develop food allergies, focusing on indoor exposures and microbes.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11450430

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.