Ultrasound-enhanced guidance for minimally invasive surgery

A clinical platform for ultrasound-augmented laparoscopy

['FUNDING_R01'] · CHILDREN'S RESEARCH INSTITUTE · NIH-11308637

This project creates a system that overlays ultrasound onto the surgeon’s laparoscopic video to help surgeons better see internal anatomy during operations on children.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorCHILDREN'S RESEARCH INSTITUTE (nih funded)
Locations1 site (WASHINGTON, UNITED STATES)
Trial IDNIH-11308637 on ClinicalTrials.gov

What this research studies

If your child needs minimally invasive (laparoscopic) surgery, this project aims to combine the camera view and a small ultrasound probe into a single, easy-to-read display so the surgeon can see both surfaces and internal structures at once. The team develops hardware and software to align (calibrate) the images in real time, track needles during ablation, and present the information as augmented reality directly in the surgeon’s view. The group has already used prototypes in 11 human cases at two surgical centers and will expand testing, refine the system, and collect safety and performance data during real operations. The goal is to make complex procedures more precise and reduce guesswork for surgeons and families.

Who could benefit from this research

Good fit: Children (including infants and those up to about 11 years old) who are scheduled for laparoscopic procedures that use intraoperative ultrasound or involve needle ablation are the most likely candidates.

Not a fit: Patients who will not have laparoscopic surgery (for example those undergoing open surgery) or procedures that do not use intraoperative ultrasound would not benefit directly from this system.

Why it matters

Potential benefit: If successful, this could help surgeons find and treat targets more accurately during laparoscopic procedures, potentially lowering complications and improving outcomes for pediatric patients.

How similar studies have performed: Early testing and prior prototypes have been used in 11 human cases showing technical feasibility and promise, but larger clinical evaluations are still limited.

Where this research is happening

WASHINGTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.