Ultra-small wearable glucose and metabolic sensor

Optimizing A Miniaturized and Integrated Continuous Glucose Monitoring Platform

NIH-funded research Integrated Medical Sensors · NIH-11193519

A very small, affordable wearable device that continuously measures glucose (and eventually ketones, temperature, and pH) for people with diabetes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIntegrated Medical Sensors NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-11193519 on NIH RePORTER

What this research studies

This project is building a tiny, on-skin device that would track my glucose and temperature and later versions may track ketones and pH. The design uses a digital semiconductor chip and flexible electronics to improve signal quality and perform on-chip temperature calibration so readings stay accurate during exercise, sleep, or illness. The team has already run a first-in-human feasibility test and will refine the sensors and manufacturing to make the device more reliable and much cheaper to produce. If successful, the device aims to be less obtrusive and more affordable than many current continuous glucose monitors.

Who could benefit from this research

Good fit: People with diabetes who use or want continuous glucose monitoring and who are willing to attend study visits (likely near the sponsor's sites) are the most likely candidates.

Not a fit: People without diabetes, those who do not want wearable sensors, or those with skin conditions that prevent device wear are unlikely to benefit directly.

Why it matters

Potential benefit: This could make continuous glucose monitoring smaller, more accurate for low blood sugar, and more affordable for people with diabetes.

How similar studies have performed: Commercial CGMs have improved diabetes care, and this miniaturized digital-sensor approach is novel but has already shown feasibility in an early human test.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.