NIH-funded research U01 cooperative agreement

Uganda Schistosomiasis Multidisciplinary Research Center

Official title: Uganda Schistosomiasis Multidisciplinary Research Centre (U-SMRC)

Funded at Uganda Virus Research Institute · NIH-11529105 · Data updated 2026-11-12

A Uganda-based research program aims to understand why some people get more severe schistosomiasis and to find better ways to prevent and control it for communities in Uganda and similar regions.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUganda Virus Research Institute
NIH-funded
Lab location1 site (Entebbe, Uganda)
Project startMay 1, 2025
Project endApril 30, 2027
Funding year2026
Award (this year)$275,225
NIH project number3U01AI168609-05S1
Project IDNIH-11529105 on NIH RePORTER

Who could benefit from this research

Could help

Children under 11 and adults with or at risk of schistosomiasis in the Lake Albert region and other endemic areas in Uganda.

Less likely to help

Individuals without Schistosoma mansoni exposure or those not enrolled in study cohorts may not directly benefit.

What this research studies

This project builds a Uganda-focused network to study schistosomiasis, with a special emphasis on severe disease. It will follow both preschool-age children and adults to understand biological factors that influence morbidity. The team will look at how the parasite, the human host, and the snail host interact at different life stages to cause worse outcomes, with careful observation and data collection across sites in Uganda.

Why it matters

Potential benefit: If successful, the work could lead to earlier detection of those at risk and more effective prevention and control strategies for schistosomiasis in Uganda and similar endemic areas.

How similar studies have gone: Past schistosomiasis research in the region has advanced understanding of morbidity patterns, and this study extends that work with multidisciplinary cohorts.

Where this research is happening

  • Uganda Virus Research Institute
    Entebbe, Uganda
    Active

Researchers

  • Principal investigator: Elliott, Alison — Uganda Virus Research Institute
  • Study coordinator: Elliott, Alison

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.