Type 2 diabetes in children and teens
Understanding and Targeting the Pathophysiology of Youth-onset Type 2 Diabetes- NYU Clinical Center
This project looks at how puberty, weight, and other personal and social factors lead to type 2 diabetes in children and teens so better prevention and treatment can be found.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11285375 on NIH RePORTER |
What this research studies
If you join, researchers will follow children and teens through puberty to track changes in blood sugar, insulin levels, and beta-cell function over time. They will collect blood tests, body measurements, and questionnaires about behavior, mental health, and social and environmental factors to see which things raise or lower risk. The team will compare boys and girls and participants from different communities (urban and rural) to map who progresses from normal blood sugar to prediabetes and youth-onset type 2 diabetes. That information will help point to modifiable risks that could be targeted to prevent or better treat diabetes in young people.
Who could benefit from this research
Good fit: Children and adolescents, especially those who are overweight or obese, have a family history of diabetes, or show signs of prediabetes and are entering or going through puberty, would be ideal candidates.
Not a fit: Adults with type 2 diabetes that began in adulthood or people without risk factors for youth-onset type 2 diabetes are unlikely to directly benefit from participating in this project.
Why it matters
Potential benefit: If successful, this work could lead to earlier detection, tailored prevention strategies, and more effective treatments for children and teens at risk of type 2 diabetes.
How similar studies have performed: Prior pediatric diabetes research (for example the TODAY study) improved understanding but left important gaps in why some youth lose beta-cell function, so this project builds on existing work to fill those gaps.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Gallagher, Mary Patricia — New York University School of Medicine
- Study coordinator: Gallagher, Mary Patricia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.