Two ways to spread a program that reduces unnecessary antibiotics for bladder bacteria
A Cluster Randomized Trial of Two Implementation Strategies to Disseminate a Successful Antibiotic Stewardship Intervention
This compares two approaches to help hospitals and nursing homes stop giving antibiotics to people who have bacteria in their urine but no symptoms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11341213 on NIH RePORTER |
What this research studies
You would hear about a proven hospital intervention that aims to avoid treating harmless bacteria in the bladder (asymptomatic bacteriuria) with antibiotics. Hospitals and nursing homes are randomized as groups to use either a virtual learning collaborative with shared group learning or individualized technical assistance on request. The project tracks how these approaches change local practices like urine testing and antibiotic prescribing and looks at patient outcomes and antibiotic use over time. The goal is to find the most practical way to spread a program that reduces needless antibiotic exposure in real-world care settings.
Who could benefit from this research
Good fit: People cared for in participating hospitals or nursing homes who have bacteria in their urine without urinary symptoms (asymptomatic bacteriuria) are the patients most directly affected by this work.
Not a fit: Patients with true urinary tract infections that cause symptoms, or people not treated at participating facilities, are unlikely to benefit from this project.
Why it matters
Potential benefit: If successful, this could lower unnecessary antibiotic use, reducing side effects and the risk of antibiotic resistance for many patients.
How similar studies have performed: Earlier work by the team showed the stewardship intervention can reduce unnecessary treatment of asymptomatic bacteriuria, but comparing large-scale rollout methods is a new step.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Trautner, Barbara Wells — Baylor College of Medicine
- Study coordinator: Trautner, Barbara Wells
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.