Two-layer breast X-ray detector to make mammograms clearer

A direct-indirect dual-layer flat-panel detector for breast cancer detection

NIH-funded research State University New York Stony Brook · NIH-11308315

Building a new dual-layer detector to create clearer, perfectly aligned 3D mammogram images for people getting breast screening, diagnosis, or treatment follow-up.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University New York Stony Brook NIH-funded
Lab location1 site (Stony Brook, United States)
Project IDNIH-11308315 on NIH RePORTER

What this research studies

You would be part of work that builds a new two-layer flat-panel detector that captures two X-ray energy images in a single exposure to avoid motion blur. The team will design and fabricate a prototype detector, then develop image-processing methods for spectral tomosynthesis with and without contrast dye. The prototype will be integrated with a clinical digital breast tomosynthesis (DBT) machine and tested first on phantoms and then in patient imaging studies. If you participate, you may have additional imaging performed using the new detector during your clinical visit.

Who could benefit from this research

Good fit: Ideal candidates are people undergoing breast cancer screening, diagnostic DBT, or imaging to monitor treatment who can attend the clinical imaging site and consent to additional imaging.

Not a fit: People who are not undergoing breast imaging, who cannot undergo DBT or contrast-enhanced imaging (for example due to allergy or pregnancy), or who live far from the clinical site are unlikely to benefit directly.

Why it matters

Potential benefit: If successful, this could produce artifact-free spectral DBT images that improve breast cancer detection, diagnosis, and treatment monitoring.

How similar studies have performed: Dual-energy and spectral breast imaging approaches have shown promise in prior work, but this specific dual-layer detector approach is a novel method designed to eliminate motion artifacts and enable perfectly registered spectral images.

Where this research is happening

Stony Brook, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast Cancer DetectionBreast Cancer TreatmentBreast cancer screening
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.