TrialNet coordination to prevent or delay type 1 diabetes
Data Coordinating Center for Type 1 Diabetes TrialNet
['FUNDING_U01'] · UNIVERSITY OF SOUTH FLORIDA · NIH-11215477
This program runs clinical trials of treatments designed to preserve insulin-producing cells in people at high risk for or recently diagnosed with type 1 diabetes.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTH FLORIDA (nih funded) |
| Locations | 1 site (TAMPA, UNITED STATES) |
| Trial ID | NIH-11215477 on ClinicalTrials.gov |
What this research studies
From a patient perspective, the coordinating center organizes and supports prevention and early-intervention trials that aim to keep your insulin-producing beta cells working. The center manages data, biostatistics, site monitoring, lab coordination, and communications among many participating clinics and laboratories. It helps design study procedures, collects clinical and lab samples, analyzes results, and shares findings through reports and publications. If you join a TrialNet study you would visit a participating center, provide samples, and follow a treatment and monitoring schedule as part of the research.
Who could benefit from this research
Good fit: People at elevated risk for type 1 diabetes (for example, with positive autoantibodies or a family history) and those recently diagnosed with type 1 diabetes are the typical candidates for TrialNet studies.
Not a fit: People with long-standing type 1 diabetes or without autoimmune markers related to type 1 diabetes are unlikely to benefit from these prevention-focused trials.
Why it matters
Potential benefit: If successful, this work could lead to treatments that delay or prevent type 1 diabetes or preserve insulin production, reducing the burden of disease.
How similar studies have performed: Related immunotherapy trials, such as teplizumab in high-risk individuals, have shown the approach can delay onset in some people, though many interventions remain experimental.
Where this research is happening
TAMPA, UNITED STATES
- UNIVERSITY OF SOUTH FLORIDA — TAMPA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KRISCHER, JEFFREY P — UNIVERSITY OF SOUTH FLORIDA
- Study coordinator: KRISCHER, JEFFREY P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brittle Diabetes Mellitus