Treatment of infections in wounds using nanospray technology
Official title: Nanospray treatment of biofilm infections in wounds
Funded at Rutgers, the State Univ of N.j. · NIH-11076666 · Data updated 2026-11-12
This study is testing a new nanospray treatment designed to help people with stubborn wounds, like burns or pressure ulcers, by breaking down harmful bacteria clusters that slow down healing, making it easier for medicines to work and helping you recover better.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project start | April 18, 2024 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $223,459 |
| NIH project number | 5R21AI169045-02 |
| Project ID | NIH-11076666 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from chronic non-healing wounds, such as those with severe burns, pressure ulcers, or surgical site infections.
✕Less likely to help
Patients with acute wounds that are healing normally or those without biofilm-related complications may not benefit from this research.
What this research studies
This research investigates a novel nanospray treatment aimed at addressing microbial biofilm infections that complicate wound healing. Biofilms, which are clusters of bacteria that adhere to surfaces, can significantly hinder recovery from wounds such as burns, pressure ulcers, and surgical sites. The approach focuses on using surfactants to enhance the penetration of therapeutic agents through the biofilm's protective layers, potentially improving treatment outcomes for patients with chronic wounds. By targeting the underlying biofilm, the research aims to reduce antibiotic resistance and promote effective healing.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for chronic wounds, reducing complications and improving healing rates.
How similar studies have gone: Previous research has shown promise in using surfactants to disrupt biofilms, indicating that this approach may be effective, though the specific application of nanospray technology is relatively novel.
Where this research is happening
-
Rutgers, the State Univ of N.j.
Piscataway, United States Active
Researchers
- Principal investigator: Roth, Charles M. — Rutgers, the State Univ of N.j.
- Study coordinator: Roth, Charles M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.