Treating PTSD to lower heart disease risk in veterans

Evidence-based Treatment for PTSD and Cardiovascular Disease Risk

NIH-funded research University of California Los Angeles · NIH-11264826

This project looks at whether effective PTSD treatments can reduce heart disease and death risk for veterans with PTSD.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11264826 on NIH RePORTER

What this research studies

If you are a veteran with PTSD and receive care in the VA, researchers will use VA medical records to see how PTSD treatments relate to later heart disease and survival. They will use a huge database with up to 20 years of records from over 2 million veterans and computer algorithms that read clinic notes to find who got psychotherapy and who took antidepressants. They will also track changes in PTSD symptoms on routine self-report measures and link those changes to diagnoses of cardiovascular disease and to death records. This is an observational analysis of existing health records rather than a new treatment program you would attend.

Who could benefit from this research

Good fit: Veterans with a documented diagnosis of PTSD who receive care in the U.S. Department of Veterans Affairs and have records of psychotherapy or antidepressant treatment are the population studied.

Not a fit: People who are not veterans, do not get care in the VA system, or lack documented PTSD treatment in their VA records would not be included and would not directly benefit from this project.

Why it matters

Potential benefit: If successful, this work could show that treating PTSD lowers the chance of heart disease and death, guiding care priorities for veterans with PTSD.

How similar studies have performed: Past research links PTSD to higher heart disease risk, but no large study has yet shown that receiving evidence-based PTSD treatment reduces cardiovascular disease or mortality, so this is a novel, large-scale analysis.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.