Transnasal esophageal heart ultrasound to reduce sedation

Trans Nasal Transesophageal Echocardiography

NIH-funded research Utah State Higher Education System--University of Utah · NIH-11306730

A new method to get detailed heart ultrasound through the nose for adults that may avoid heavy sedation.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUtah State Higher Education System--University of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-11306730 on NIH RePORTER

What this research studies

Right now, the usual esophageal heart ultrasound (TEE) goes down the throat and often requires sedation, which raises risks and delays care. This project is adapting the probe to pass through the nose (anterior nares) so images of posterior heart structures like the mitral valve and left atrial appendage can be obtained without general sedation. Doctors will use a smaller, transnasal approach and compare image quality, patient comfort, and safety to standard TEE. The goal is to make high-quality heart imaging faster, safer, and more available to adults who need it.

Who could benefit from this research

Good fit: Adults (21+) who need transesophageal echocardiography for conditions like valve disease, endocarditis, or perioperative cardiac evaluation and who can tolerate a transnasal procedure are ideal candidates.

Not a fit: Patients with severe nasal obstruction, active nasal or esophageal bleeding, uncorrected coagulopathy, or other contraindications to transnasal or transesophageal probes may not benefit from this approach.

Why it matters

Potential benefit: If successful, this could let patients get high-quality TEE images with less or no sedation, lowering risk, cost, and delays.

How similar studies have performed: Small feasibility reports and pilot work with smaller probes suggest transnasal TEE can work, but it is not widely adopted and larger clinical testing is still limited.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.