Transforming ticks to understand disease transmission
Germline Transformation of Ticks
This study is looking at ways to change ticks at a genetic level to learn more about how they live and spread diseases like Lyme disease, which could help find better ways to control ticks and protect people and animals from these illnesses.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nevada Reno NIH-funded |
| Lab location | 1 site (Reno, United States) |
| Project ID | NIH-11062372 on NIH RePORTER |
What this research studies
This research focuses on genetically transforming ticks to better understand their biology and the diseases they transmit, such as Lyme disease. By utilizing advanced gene-editing techniques like CRISPR/Cas9, the researchers aim to develop new methods for controlling tick populations and the pathogens they carry. The project involves overcoming technical challenges related to tick embryology to enable effective gene editing. Patients and livestock affected by tick-borne diseases could benefit from the insights gained through this research.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals at risk of Lyme disease and livestock farmers affected by tick infestations.
Not a fit: Patients who are not at risk for tick-borne diseases or do not have livestock may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for controlling tick populations and reducing the incidence of tick-borne diseases.
How similar studies have performed: While gene-editing approaches in ticks are relatively novel, similar techniques have shown promise in other arthropod vectors, indicating potential for success.
Where this research is happening
Reno, United States
- University of Nevada Reno — Reno, United States (Active)
Researchers
- Principal investigator: Gulia-Nuss, Monika — University of Nevada Reno
- Study coordinator: Gulia-Nuss, Monika
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.