Transdiagnostic study on emotional impulsivity linked to suicidal thoughts and behavior
Official title: A Transdiagnostic Study of Emotional Impulsivity in Suicidal Ideation and Behavior
Funded at New York University School of Medicine · NIH-11355608 · Data updated 2026-11-12
A study in people with schizophrenia spectrum disorder and major depressive disorder will examine how emotionally driven impulsivity and brain activity relate to suicidal thoughts and past attempts.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $791,913 |
| NIH project number | 5R01MH136161-03 |
| Project ID | NIH-11355608 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with schizophrenia spectrum disorder or major depressive disorder who have current or past suicidal thoughts or behaviors.
✕Less likely to help
Individuals without SSD or MDD or without any history of suicidality may have limited direct benefit.
What this research studies
This project will recruit people with SSD and MDD to explore how urgency-based impulsivity connects with brain regions involved in emotion and decision-making. They will use questionnaires and brain imaging to track how these factors relate to suicidal ideation and history of attempts. The goal is to identify neural and psychological markers that could inform future prevention and treatment for those at risk. Findings may guide personalized approaches to reduce impulsive risk and improve mental health care for affected patients.
Why it matters
Potential benefit: If successful, the work could lead to earlier identification of individuals at higher risk for suicidality and inform targeted interventions.
How similar studies have gone: Previous work linked urgency-related impulsivity to suicide risk and corresponding brain activity, supporting potential translational value.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Hoptman, Matthew J — New York University School of Medicine
- Study coordinator: Hoptman, Matthew J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.