NIH-funded research R01 grant

Training to manage pain after breast cancer surgery

Official title: Persistent Post-Mastectomy Pain: Randomized Clinical Trial of Targeted Pain Coping Skills Training (Targeted-PCST) with Mediational Analysis

Funded at Duke University · NIH-10889926 · Data updated 2026-11-12

This study is looking at how teaching women with ongoing pain after breast cancer surgery some helpful ways to cope with that pain can make them feel better both emotionally and physically.

More Mastectomy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startApril 1, 2020
Project endMarch 31, 2026
Funding year2024
Award (this year)$590,996
NIH project number5R01CA249959-05
Project IDNIH-10889926 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are women who have undergone mastectomy or lumpectomy and are experiencing persistent pain post-surgery.

Less likely to help

Patients who have not had breast cancer surgery or those without persistent pain may not benefit from this research.

What this research studies

This research investigates how targeted pain coping skills training can help women experiencing persistent pain after breast cancer surgery. It aims to understand the psychological factors that contribute to ongoing pain and whether improving coping skills can alleviate this discomfort. Participants will engage in training designed to enhance their ability to manage pain through non-pharmacological methods, potentially leading to better emotional and physical functioning. The study will also analyze how factors like pain catastrophizing and self-efficacy influence pain outcomes.

Why it matters

Potential benefit: If successful, this research could provide effective non-drug strategies for managing persistent pain after breast cancer surgery.

How similar studies have gone: Previous research has shown promise in using psychosocial interventions to manage chronic pain, suggesting potential success for this approach.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Shelby, Rebecca a — Duke University
  • Study coordinator: Shelby, Rebecca a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.