Training to improve cognitive function in people recovering from COVID-19.

Cognitive strategy training in Post-COVID-19 Syndrome: A feasibility trial.

NIH-funded research University of Missouri-Columbia · NIH-10712171

This study is looking to help people who are having trouble with thinking and daily activities after having COVID-19 by testing a remote training program that teaches new ways to manage everyday tasks and improve brain function.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Missouri-Columbia NIH-funded
Lab location1 site (Columbia, United States)
Project IDNIH-10712171 on NIH RePORTER

What this research studies

This research aims to enhance recovery from cognitive impairments experienced by individuals suffering from post-COVID-19 syndrome (PCS). It will investigate the feasibility of a remote training program called the Cognitive Orientation to daily Occupational Performance (CO-OP), which focuses on helping participants develop new strategies to manage daily activities and improve cognitive function. Participants will be randomly assigned to either the CO-OP training group or an inactive control group, with assessments conducted to measure the impact on their daily living activities and overall quality of life.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing cognitive impairments due to post-COVID-19 syndrome.

Not a fit: Patients who do not have cognitive impairments related to post-COVID-19 syndrome may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide effective strategies for improving cognitive function and daily living skills in individuals recovering from COVID-19.

How similar studies have performed: Previous research has shown promise in using cognitive training strategies for rehabilitation, suggesting potential success for this approach.

Where this research is happening

Columbia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.