Training the brain to improve response control in people with obsessive-compulsive disorder

Neural Mechanisms of Response Inhibition Training for Obsessive-Compulsive Disorder and Related Conditions

NIH-funded research University of Wisconsin Milwaukee · NIH-10950397

This study is looking at whether a new computer training program can help people with obsessive-compulsive disorder (OCD) and similar issues better control their impulses, and it involves comparing those who use the training with those who don’t to see how it affects their brain activity and symptoms.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin Milwaukee NIH-funded
Lab location1 site (Milwaukee, United States)
Project IDNIH-10950397 on NIH RePORTER

What this research studies

This research investigates how a new computerized training program can help individuals with obsessive-compulsive disorder (OCD) and related conditions improve their ability to control impulsive responses. The study will involve participants undergoing a randomized trial where some will receive the training while others will receive a placebo. Researchers will measure changes in brain activity related to response inhibition before and after the training to understand its effectiveness. The goal is to find a lasting treatment that can significantly reduce symptoms associated with these disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with obsessive-compulsive disorder, trichotillomania, or skin picking disorder.

Not a fit: Patients who do not have obsessive-compulsive disorder or related conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for individuals struggling with OCD and related disorders.

How similar studies have performed: Previous research has shown promise in using cognitive training methods to improve response inhibition, suggesting potential success for this novel approach.

Where this research is happening

Milwaukee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Attention deficit hyperactivity disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.