Training the brain to improve response control in people with obsessive-compulsive disorder
Official title: Neural Mechanisms of Response Inhibition Training for Obsessive-Compulsive Disorder and Related Conditions
Funded at University of Wisconsin Milwaukee · NIH-10950397 · Data updated 2026-11-12
This study is looking at whether a new computer training program can help people with obsessive-compulsive disorder (OCD) and similar issues better control their impulses, and it involves comparing those who use the training with those who don’t to see how it affects their brain activity and symptoms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin Milwaukee NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $828,787 |
| NIH project number | 4R33MH125127-03 |
| Project ID | NIH-10950397 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with obsessive-compulsive disorder, trichotillomania, or skin picking disorder.
✕Less likely to help
Patients who do not have obsessive-compulsive disorder or related conditions may not benefit from this research.
What this research studies
This research investigates how a new computerized training program can help individuals with obsessive-compulsive disorder (OCD) and related conditions improve their ability to control impulsive responses. The study will involve participants undergoing a randomized trial where some will receive the training while others will receive a placebo. Researchers will measure changes in brain activity related to response inhibition before and after the training to understand its effectiveness. The goal is to find a lasting treatment that can significantly reduce symptoms associated with these disorders.
Why it matters
Potential benefit: If successful, this research could provide a new, effective treatment option for individuals struggling with OCD and related disorders.
How similar studies have gone: Previous research has shown promise in using cognitive training methods to improve response inhibition, suggesting potential success for this novel approach.
Where this research is happening
-
University of Wisconsin Milwaukee
Milwaukee, United States Active
Researchers
- Principal investigator: Lee, Han Joo — University of Wisconsin Milwaukee
- Study coordinator: Lee, Han Joo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.