Training scientists to improve heart drug safety for children
Official title: Mentoring in Pediatric Cardiovascular Pharmacology and Early Phase Trials
Funded at Duke University · NIH-11045069 · Data updated 2026-11-12
This study is all about making heart medications safer and more effective for kids by training new scientists to understand how these drugs work in young patients, so we can improve treatments for children, especially those who are very sick.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $121,059 |
| NIH project number | 5K24HL173596-02 |
| Project ID | NIH-11045069 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children with cardiovascular conditions, particularly those under 21 years old who may require specialized drug treatments.
✕Less likely to help
Patients with cardiovascular conditions who are older than 21 years may not benefit directly from this research.
What this research studies
This research focuses on addressing the significant gap in pediatric cardiovascular pharmacology, particularly the lack of properly studied heart medications for children. It aims to train and mentor new scientists in evaluating how these drugs work in young patients, using advanced modeling techniques to ensure safer and more effective treatments. By leveraging real-world data and innovative trial designs, the project seeks to improve drug labeling and reduce the risks associated with off-label drug use in pediatric patients. The ultimate goal is to enhance the safety and efficacy of cardiovascular drugs for children, particularly those in critical care settings.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective heart medications specifically designed for children.
How similar studies have gone: Other research has shown success in improving pediatric drug safety through targeted training and innovative methodologies, indicating a promising approach.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Hornik, Christoph — Duke University
- Study coordinator: Hornik, Christoph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.