NIH-funded research Sbir 2 grant

Training program to help manage chronic pain using computer technology

Official title: Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)

Funded at Evon Medics, LLC · NIH-11053642 · Data updated 2026-11-12

This study is testing a new, easy-to-use program that you can use at home to help manage chronic pain and improve your mood and thinking skills, making it easier to cope with the challenges that come with living with pain.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionEvon Medics, LLC
NIH-funded
Lab location1 site (Elkridge, United States)
Project startSeptember 20, 2022
Project endFebruary 28, 2026
Funding year2025
Award (this year)$1,280,870
NIH project number5R44NS125745-03
Project IDNIH-11053642 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing chronic pain, particularly those also dealing with anxiety, depression, or cognitive impairments.

Less likely to help

Patients with acute pain or those who do not experience any emotional or cognitive challenges related to their pain may not benefit from this research.

What this research studies

This research focuses on developing a user-friendly, home-based platform that utilizes computerized training to help manage chronic pain and its associated emotional and cognitive challenges. By targeting the brain's orbitofrontal networks, the program aims to improve pain management and reduce negative feelings such as anxiety and depression. Patients will engage in neuromodulatory training designed to enhance their emotional and cognitive functions, potentially leading to better pain control. The approach is based on scientific findings that chronic pain can affect brain structure and function.

Why it matters

Potential benefit: If successful, this research could provide a new, effective, and non-invasive treatment option for individuals suffering from chronic pain and related emotional issues.

How similar studies have gone: While the specific approach of computerized chemosensory training is novel, similar neuromodulatory techniques have shown promise in managing chronic pain and associated conditions in previous studies.

Where this research is happening

  • Evon Medics, LLC
    Elkridge, United States
    Active

Researchers

  • Principal investigator: Nwaokobia, Charles Chiedu — Evon Medics, LLC
  • Study coordinator: Nwaokobia, Charles Chiedu

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.