Tracking viruses in children to improve vaccine effectiveness

IP21-002 US Enhanced Surveillance Network to Assess Burden, Natural History, and Effectiveness of Vaccines to Prevent Enteric and Respiratory Viruses in Children

NIH-funded research Cincinnati Childrens Hosp Med Ctr · NIH-11046450

This study is looking to gather information from children's hospitals across the U.S. to see how different viruses that make kids sick, like norovirus and flu, are affecting them, which will help improve vaccines and keep kids healthier.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionCincinnati Childrens Hosp Med Ctr NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-11046450 on NIH RePORTER

What this research studies

This research aims to establish a network of pediatric hospitals across the United States to monitor and assess the impact of various viruses that cause respiratory and gastrointestinal illnesses in children. By conducting active surveillance in emergency departments and inpatient settings, the study will collect data on infections caused by viruses such as norovirus, rotavirus, and influenza, as well as healthy controls. The findings will help inform vaccine recommendations and evaluate the effectiveness of current vaccination programs against these viruses.

Who could benefit from this research

Good fit: Ideal candidates for participation include children under 18 years of age who are seeking healthcare for respiratory or gastrointestinal symptoms, as well as healthy children for comparison.

Not a fit: Patients who are not children or those who do not seek care for viral infections may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved vaccine strategies that better protect children from serious viral infections.

How similar studies have performed: Previous research has shown success in using surveillance networks to improve public health responses to infectious diseases, indicating that this approach is both tested and effective.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.