Tracking vaccine-preventable gut and breathing viruses in children in Seattle
IP21-002, Enhanced Surveillance to Assess Vaccine Preventable Enteric and Respiratory Virus Illnesses
This project tracks viruses that cause stomach and breathing illnesses in children and checks how well vaccines like flu and rotavirus protect them.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Children's Hospital NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11138413 on NIH RePORTER |
What this research studies
We will enroll children seen in the hospital, emergency department, and healthy controls at Seattle Children’s Hospital and affiliated clinics in King and Snohomish counties. Families will be asked about symptoms and vaccine history, and respiratory swabs or stool samples will be collected from children as appropriate. Samples will be tested with molecular PCR methods to identify viruses, and vaccination records will be checked in the state vaccine database. During COVID-19, options like phone or online consent and home specimen collection may be used to make participation easier.
Who could benefit from this research
Good fit: Ideal candidates are children (hospitalized, emergency department patients, or healthy controls) in King and Snohomish counties whose parents or guardians can consent and provide vaccine history and specimens.
Not a fit: Adults, children outside the Seattle metropolitan area, and anyone unwilling to provide vaccine information or biological samples would not be eligible to participate or benefit directly.
Why it matters
Potential benefit: If successful, this work could help reduce childhood illness by pinpointing which viruses cause the most disease and where vaccines are most protective.
How similar studies have performed: Hospital- and clinic-based surveillance using PCR testing and vaccine registry data has been used successfully before to measure virus burden and vaccine impact, so the approach is established.
Where this research is happening
Seattle, United States
- Seattle Children's Hospital — Seattle, United States (Active)
Researchers
- Principal investigator: Englund, Janet a — Seattle Children's Hospital
- Study coordinator: Englund, Janet a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.