Tracking tumor movement during radiation therapy using real-time imaging.

Real time scattered x-ray imaging for tumor motion tracking in radiotherapy.

['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-11098758

This study is testing a new way to make lung cancer radiation treatment safer and more effective by using special x-ray imaging to follow the tumor as it moves, which could help protect healthy tissue and reduce side effects for patients receiving stereotactic body radiotherapy (SBRT).

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-11098758 on ClinicalTrials.gov

What this research studies

This research focuses on improving the precision of radiation therapy for lung cancer by using real-time scattered x-ray imaging to track tumor movement. The goal is to reduce the margin of healthy tissue that receives radiation, thereby minimizing side effects while maximizing the dose delivered to the tumor. By adapting the radiation beam in real-time based on the tumor's position, this approach aims to enhance treatment effectiveness and patient safety. Patients undergoing stereotactic body radiotherapy (SBRT) may benefit from this innovative technique.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with lung cancer who are undergoing stereotactic body radiotherapy.

Not a fit: Patients with cancers other than lung cancer or those not receiving radiation therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective lung cancer treatments with fewer side effects for patients.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for tumor tracking, indicating potential success for this novel approach.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: anti-cancer therapy, Cancer Cause, Cancer Etiology, cancer imaging, cancer radiation therapy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.