Tracking tumor movement during radiation therapy using real-time imaging.
Official title: Real time scattered x-ray imaging for tumor motion tracking in radiotherapy.
Funded at Johns Hopkins University · NIH-11098758 · Data updated 2026-11-12
This study is testing a new way to make lung cancer radiation treatment safer and more effective by using special x-ray imaging to follow the tumor as it moves, which could help protect healthy tissue and reduce side effects for patients receiving stereotactic body radiotherapy (SBRT).
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | June 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $562,587 |
| NIH project number | 5R01CA285379-02 |
| Project ID | NIH-11098758 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with lung cancer who are undergoing stereotactic body radiotherapy.
✕Less likely to help
Patients with cancers other than lung cancer or those not receiving radiation therapy may not benefit from this research.
What this research studies
This research focuses on improving the precision of radiation therapy for lung cancer by using real-time scattered x-ray imaging to track tumor movement. The goal is to reduce the margin of healthy tissue that receives radiation, thereby minimizing side effects while maximizing the dose delivered to the tumor. By adapting the radiation beam in real-time based on the tumor's position, this approach aims to enhance treatment effectiveness and patient safety. Patients undergoing stereotactic body radiotherapy (SBRT) may benefit from this innovative technique.
Why it matters
Potential benefit: If successful, this research could lead to more effective lung cancer treatments with fewer side effects for patients.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for tumor tracking, indicating potential success for this novel approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Jia, Xun — Johns Hopkins University
- Study coordinator: Jia, Xun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.