Tracking T Cell Cancer Treatment with Nanoparticles
Nanoparticles to Track T Cell Immunotherapy Using Magnetic Particle Imaging
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-11035057
This project aims to find better ways to see where cancer-fighting T cells go in the body using tiny magnetic particles and a special imaging method.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-11035057 on ClinicalTrials.gov |
What this research studies
When T cells are used to fight cancer, it's important to know if they reach the tumor and stay there, and if they avoid harming healthy tissues. This project is developing a new imaging technique called magnetic particle imaging (MPI) to precisely track these T cells in the body. Researchers are creating special nanoparticles that attach to T cells, allowing doctors to see their exact location and how many are present. This improved tracking could help make T cell therapies safer and more effective for people with solid cancers.
Who could benefit from this research
Good fit: Patients receiving T cell immunotherapy for solid cancers could eventually benefit from this improved tracking technology.
Not a fit: Patients not undergoing T cell immunotherapy or those with cancers not treated by this method would not directly benefit from this specific tracking technology.
Why it matters
Potential benefit: If successful, this work could lead to more effective and safer T cell immunotherapies by allowing doctors to precisely monitor treatment and adjust it as needed.
How similar studies have performed: While T cell immunotherapy is an established treatment, this specific magnetic particle imaging approach for tracking T cells is a novel and developing technique.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RINALDI-RAMOS, CARLOS M — UNIVERSITY OF FLORIDA
- Study coordinator: RINALDI-RAMOS, CARLOS M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Model, Cancer Treatment