NIH-funded research U01 cooperative agreement

Tracking respiratory viruses and immune responses in blood donors across the nation

Official title: RFA-IP-24-046: Nationwide Cohort of Blood Donors to Estimate Burden of Respiratory Viruses and Immunologic Response

Funded at Vitalant · NIH-11036930 · Data updated 2026-11-12

This study is looking at blood samples from over 30,000 donors to understand how common respiratory viruses are and how our immune systems respond to them, helping us learn more about these viruses across the country.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionVitalant
NIH-funded
Lab location1 site (Scottsdale, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2029
Funding year2024
Award (this year)$4,500,000
NIH project number1U01IP001266-01
Project IDNIH-11036930 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation are healthy individuals who regularly donate blood and are willing to provide additional samples for research purposes.

Less likely to help

Patients who are not blood donors or those with underlying health conditions that prevent them from donating blood may not benefit from this research.

What this research studies

This research involves a nationwide cohort of blood donors who will provide blood samples to help estimate the burden of respiratory viruses and the immune responses to them. The study will collect and analyze samples from at least 30,000 donors, assessing antibody prevalence and infection rates quarterly. By utilizing advanced testing methods and a large database of donor information, the research aims to provide valuable insights into respiratory virus trends and immune responses across different regions. This approach leverages the unique access to blood donor samples and data from major blood collection organizations.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of respiratory viruses and improve public health responses to viral outbreaks.

How similar studies have gone: Previous studies utilizing blood donor cohorts have successfully provided insights into epidemiology and public health, indicating that this approach has a track record of success.

Where this research is happening

  • Vitalant
    Scottsdale, United States
    Active

Researchers

  • Principal investigator: Busch, Michael Paul — Vitalant
  • Study coordinator: Busch, Michael Paul

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Browse more
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.