Tracking pancreas health in people at risk for type 1 diabetes
Official title: Longitudinal PET/MRI assessment of the pancreas in individuals at risk for and with recent onset type 1 diabetes
Funded at Yale University · NIH-11047943 · Data updated 2026-11-12
This study is looking at how the pancreas works in people who might be at risk for or have just started to develop type 1 diabetes, using special imaging tools to track changes in insulin production and pancreatic health over time, so we can learn more about the disease and how new treatments might help.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | March 13, 2025 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $669,342 |
| NIH project number | 1R01DK139213-01A1 |
| Project ID | NIH-11047943 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for type 1 diabetes and those who have recently been diagnosed.
✕Less likely to help
Patients with established type 1 diabetes who are not in the early stages of the disease may not benefit from this research.
What this research studies
This research investigates how the pancreas functions in individuals who are at risk for or have recently developed type 1 diabetes. Using advanced imaging techniques like PET and MRI, the study aims to measure important factors such as insulin vesicle functional capacity and beta cell mass over time. By monitoring these changes, researchers hope to better understand the progression of diabetes and the effectiveness of new therapies. Participants will undergo imaging assessments to provide valuable data on their pancreatic health.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment strategies for individuals with type 1 diabetes.
How similar studies have gone: Previous research has shown promise in using imaging techniques to assess pancreatic function, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Bini, Jason — Yale University
- Study coordinator: Bini, Jason
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.