Tracking pancreas health in people at risk for type 1 diabetes
Longitudinal PET/MRI assessment of the pancreas in individuals at risk for and with recent onset type 1 diabetes
This study is looking at how the pancreas works in people who might be at risk for or have just started to develop type 1 diabetes, using special imaging tools to track changes in insulin production and pancreatic health over time, so we can learn more about the disease and how new treatments might help.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11047943 on NIH RePORTER |
What this research studies
This research investigates how the pancreas functions in individuals who are at risk for or have recently developed type 1 diabetes. Using advanced imaging techniques like PET and MRI, the study aims to measure important factors such as insulin vesicle functional capacity and beta cell mass over time. By monitoring these changes, researchers hope to better understand the progression of diabetes and the effectiveness of new therapies. Participants will undergo imaging assessments to provide valuable data on their pancreatic health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for type 1 diabetes and those who have recently been diagnosed.
Not a fit: Patients with established type 1 diabetes who are not in the early stages of the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment strategies for individuals with type 1 diabetes.
How similar studies have performed: Previous research has shown promise in using imaging techniques to assess pancreatic function, suggesting that this approach could yield valuable insights.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Bini, Jason — Yale University
- Study coordinator: Bini, Jason
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.