NIH-funded research U01 cooperative agreement

Tracking outcomes of islet transplants for diabetes treatment

Official title: Continuation of The Collaborative Islet Transplantation Registry (CITR)

Funded at The Emmes Company, LLC · NIH-10903933 · Data updated 2026-11-12

This study is looking at how well pancreatic islet transplants work for people with Type 1 diabetes who have trouble managing their blood sugar, so we can learn more about how to help them feel better and stay healthier.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionThe Emmes Company, LLC
NIH-funded
Lab location1 site (Rockville, United States)
Project startSeptember 15, 2022
Project endJune 30, 2027
Funding year2024
Award (this year)$314,470
NIH project number5U01DK133709-03
Project IDNIH-10903933 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with Type 1 diabetes who have severe glycemic lability and may benefit from islet transplantation.

Less likely to help

Patients who do not have Type 1 diabetes or those who are not candidates for islet transplantation may not receive benefits from this research.

What this research studies

This research focuses on the Collaborative Islet Transplantation Registry, which collects and analyzes data on both allogeneic and autologous pancreatic islet transplants. The goal is to monitor the effectiveness and safety of these transplants in patients with Type 1 diabetes who experience severe blood sugar fluctuations. By collaborating with various stakeholders, the study aims to improve understanding of how these transplants can help patients regain better glycemic control. Patients' experiences and outcomes will be systematically documented to enhance future treatment approaches.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options and better management of diabetes for patients undergoing islet transplantation.

How similar studies have gone: Previous research on islet transplantation has shown promising results in improving glycemic control for patients with Type 1 diabetes, indicating that this approach has a foundation of success.

Where this research is happening

  • The Emmes Company, LLC
    Rockville, United States
    Active

Researchers

  • Principal investigator: Payne, Elizabeth Holly — The Emmes Company, LLC
  • Study coordinator: Payne, Elizabeth Holly

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.