Tracking kidney health from childhood into young adulthood
Official title: Chronic Kidney Disease in Children (CKiD V)
Funded at Children's Mercy Hosp (Kansas City, Mo) · NIH-11379172 · Data updated 2026-11-12
This project follows children and teens with chronic kidney disease to learn how kidney function and heart health change as they grow into young adults.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Mercy Hosp (Kansas City, Mo) NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project start | September 30, 2003 |
| Project end | July 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $43,639 |
| NIH project number | 3U01DK066143-23S1 |
| Project ID | NIH-11379172 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are children and adolescents with chronic kidney disease—especially teens about 14–17 years old for new enrollment and prior CKiD participants continuing into young adulthood.
✕Less likely to help
People without chronic kidney disease or those who cannot participate in remote lab visits, provide medical record access, or commit to long-term follow-up are unlikely to gain direct benefit from joining.
What this research studies
If you join, the team will continue following children already in the CKiD group and recruit teens aged about 14–17 to follow as they become young adults. Vitals and blood tests can be collected at home through national lab contractors, and health information will also be pulled from medical records between visits. You will be able to enter information online or by phone using secure tools, and the study will combine clinical data with social factors. Researchers will use statistical and machine-learning methods to find which markers and life circumstances are linked to faster kidney decline and heart problems.
Why it matters
Potential benefit: If successful, this work could help predict which young people are at higher risk of faster kidney decline and guide earlier steps to protect kidney and heart health.
How similar studies have gone: Earlier phases of the CKiD cohort and other pediatric CKD cohorts have produced useful findings about risk factors, while applying machine-learning to predict individual progression is a newer but promising approach.
Where this research is happening
-
Children's Mercy Hosp (Kansas City, Mo)
Kansas City, United States Active
Researchers
- Principal investigator: Warady, Bradley Alan — Children's Mercy Hosp (Kansas City, Mo)
- Study coordinator: Warady, Bradley Alan
Related research
Other NIH-funded projects on the same topics.
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Personalized CKD-MBD care using systems biology and AI
A patient-facing program aims to tailor mineral-balance therapy for people with chronic kidney disease by using a computer model and smart decision rules to predict who will respond best to treatments.
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This project tests a new way to prevent dangerous diabetic ketoacidosis in people with type 1 diabetes and chronic kidney disease who are using SGLT inhibitors, by tracking ketones in real time and combining glucose-keton data for safer therapy.
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Chronic Kidney Disease in Children: following young people as they grow up with CKD
A long-term study in kids with chronic kidney disease tracks kidney function and heart health as they transition into adulthood.
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Chronic Kidney Disease in Children follow-up study
A long-term study that follows kids with kidney disease as they grow into young adults, collecting health data from home and official records.
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This grant looks at why some children who have malaria develop kidney injury and later chronic kidney disease, focusing on how severe malaria affects the kidneys over time.
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Boosting self-care and physical activity for older adults with chronic kidney disease
This program helps older adults with chronic kidney disease build the skills, confidence, and motivation to be more physically active.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.