Tracking kidney health from childhood into young adulthood
Chronic Kidney Disease in Children (CKiD)
This project follows children and teens with chronic kidney disease to learn what leads to changes in their kidney function and heart health during adolescence and young adulthood.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11134447 on NIH RePORTER |
What this research studies
You or your child would continue with regular follow-up visits and the team will add new participants aged 14–17 to better watch how kidney health changes during the teen years. Vitals and blood or urine tests can be done at home through national lab contractors, and health records will be pulled from electronic medical records between visits. Participants can enter information online or by phone using REDCap, which helps combine data with other pediatric kidney groups. The researchers will use statistical and machine-learning tools to link clinical measures and social factors to later kidney and heart outcomes.
Who could benefit from this research
Good fit: Ideal participants are children and adolescents with chronic kidney disease, especially those aged about 14–17 or those already enrolled in the existing CKiD cohort.
Not a fit: People without chronic kidney disease or those unwilling to provide medical records, lab samples, or regular follow-up are unlikely to benefit from participating.
Why it matters
Potential benefit: If successful, the project could help predict who is most at risk of faster kidney decline and guide earlier, more personalized care for children with CKD.
How similar studies have performed: Long-term pediatric CKD cohorts have previously identified risk factors for progression, but combining remote home labs, EHR extraction, and machine-learning prediction across adolescence is a newer and less-tested approach.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Furth, Susan L. — Children's Hosp of Philadelphia
- Study coordinator: Furth, Susan L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.