Tracking Islet Transplants for Severe Diabetes
Official title: Continuation of The Collaborative Islet Transplantation Registry (CITR)
Funded at The Emmes Company, LLC · NIH-11144522 · Data updated 2026-11-12
This effort continues to gather important information about pancreatic islet transplantation for people with severe diabetes.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | The Emmes Company, LLC NIH-funded |
| Lab location | 1 site (Rockville, United States) |
| Project start | September 15, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $646,310 |
| NIH project number | 5U01DK133709-04 |
| Project ID | NIH-11144522 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals with Type 1 diabetes or other conditions leading to severe blood sugar instability who have undergone or are considering pancreatic islet transplantation.
✕Less likely to help
Patients who do not have severe diabetes or are not candidates for islet transplantation would not directly benefit from this registry.
What this research studies
This project maintains a central registry that collects data on patients who have received pancreatic islet transplants. The registry tracks both allogeneic (from a donor) and autologous (from one's own body) islet transplants, as well as other beta cell replacement therapies. By collecting this information, we can better understand how effective and safe these treatments are for individuals with Type 1 diabetes or those who have lost islet cell function, especially when they experience severe blood sugar fluctuations.
Why it matters
Potential benefit: If successful, this registry will provide valuable insights into the long-term outcomes and safety of islet transplantation, helping to improve future care for patients with severe diabetes.
How similar studies have gone: This is a continuation of an established registry, building upon years of data collection to further understand islet transplantation outcomes.
Where this research is happening
-
The Emmes Company, LLC
Rockville, United States Active
Researchers
- Principal investigator: Payne, Elizabeth Holly — The Emmes Company, LLC
- Study coordinator: Payne, Elizabeth Holly
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.