Tracking diabetes risk after acute pancreatitis at UF Health and AdventHealth
Official title: Continuation of Type 1 Diabetes in Acute Pancreatitis Consortium – UF Health and AdventHealth Combined Clinical Center
Funded at University of Florida · NIH-11234411 · Data updated 2026-11-12
Following people hospitalized with acute or relapsing pancreatitis to find who develops diabetes and why.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 16, 2020 |
| Project end | July 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $452,769 |
| NIH project number | 2U01DK127392-06 |
| Project ID | NIH-11234411 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults treated for acute or relapsing pancreatitis at UF Health or participating AdventHealth hospitals who can consent to follow-up visits and provide blood or tissue samples.
✕Less likely to help
People without acute pancreatitis or those who already had established diabetes before their pancreatitis episode are unlikely to benefit directly from this program.
What this research studies
If you are hospitalized with acute or relapsing pancreatitis, this program follows you over time to see who develops diabetes and what might cause it. Researchers at UF and AdventHealth enroll large numbers of patients and collect blood and other samples while performing genetic, immune, metabolic, histologic, and functional tests. They combine these lab results with clinical records and long-term follow-up visits to look for risk factors and early warning signs. An added project called DREAM-ON will provide more detailed mechanistic studies to better understand diabetes after pancreatitis.
Why it matters
Potential benefit: This work could help predict, prevent, and better treat diabetes that starts after pancreatitis.
How similar studies have gone: Smaller prior studies have linked pancreatitis to later diabetes, but this larger, long-term mechanistic cohort aims to deliver clearer and more actionable answers.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Forsmark, Christopher E — University of Florida
- Study coordinator: Forsmark, Christopher E
Related research
Other NIH-funded projects on the same topics.
-
Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth
A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.
-
Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium
A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.
-
Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford
A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.
-
Type 1 Diabetes after Acute Pancreatitis: Immune Clues from the Pacific Northwest
A multi-center study follows adults after an acute pancreatitis episode to understand how some develop Type 1 diabetes and what immune factors are involved.
-
Diabetes After Acute Pancreatitis: Understanding Progression and Genetics at Cedars-Sinai
This grant supports Cedars-Sinai’s clinical center as part of a national effort to study why some adults develop brittle type 1 diabetes after an acute pancreatitis episode and how genes influence this risk.
-
Understanding how acute pancreatitis may lead to type 1 diabetes
This study is looking at how having acute pancreatitis might lead to type 1 diabetes, and it aims to find early warning signs and risk factors to help identify people who could be at risk for developing diabetes after pancreatitis.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.