Tracking changes in walking and ankle function in young people with Charcot-Marie-Tooth disease
Official title: Longitudinal Changes in Gait and Ankle Function in Youth with Charcot-Marie-Tooth Disease
Funded at Children's Hospital of Los Angeles · NIH-10811149 · Data updated 2026-11-12
This study is looking at how walking and ankle movement change over time in young people with Charcot-Marie-Tooth disease, so we can better understand their challenges and improve their care.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hospital of Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 21, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $186,250 |
| NIH project number | 1R03NS131977-01A1 |
| Project ID | NIH-10811149 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are youth diagnosed with Charcot-Marie-Tooth disease who have previously undergone gait analysis.
✕Less likely to help
Patients who do not have Charcot-Marie-Tooth disease or those who are not within the youth age range may not benefit from this research.
What this research studies
This research investigates how walking ability and ankle function change over time in youth diagnosed with Charcot-Marie-Tooth disease (CMT). By conducting longitudinal gait analysis, the study aims to gather data on how individual characteristics, such as age and strength, influence the progression of walking difficulties. The goal is to develop predictive models that can help understand how CMT affects gait over time, ultimately improving patient care and management. Participants will undergo follow-up assessments to track their progress and identify patterns in their condition.
Why it matters
Potential benefit: If successful, this research could lead to better predictions of disease progression in young patients with CMT, allowing for more personalized treatment plans.
How similar studies have gone: Previous research has shown promise in understanding gait changes in CMT, but this longitudinal approach is relatively novel and aims to build on earlier findings.
Where this research is happening
-
Children's Hospital of Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Wren, Tishya a L — Children's Hospital of Los Angeles
- Study coordinator: Wren, Tishya a L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.