Tracking brain and development from pregnancy through early childhood

22/24 Healthy Brain and Child Development National Consortium

NIH-funded research Virginia Polytechnic Inst and St Univ · NIH-11143867

Collects brain scans, questionnaires, and biological samples from pregnant people and their children up to age 10 to learn how early-life experiences shape healthy development.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionVirginia Polytechnic Inst and St Univ NIH-funded
Lab location1 site (Blacksburg, United States)
Project IDNIH-11143867 on NIH RePORTER

What this research studies

This national effort enrolls about 7,200 mothers and their children at 27 sites across the United States and follows them from pregnancy through the first 10 years of life. Participants will be invited to have MRI and EEG brain scans, complete behavioral and developmental assessments, answer health and stress questionnaires, and provide biospecimens. The project combines these measures into a large, shared dataset to map typical brain and behavioral growth and to see how exposures like maternal substance use, toxicants, or early stress may change developmental paths. Joining typically involves scheduled in-person visits for imaging and testing, as well as periodic surveys and sample collection.

Who could benefit from this research

Good fit: Pregnant people and their infants, and children up to age 10, who can attend visits at one of the participating U.S. sites are ideal candidates.

Not a fit: People outside the enrolled age ranges or geographic areas, or those seeking immediate clinical treatment rather than research participation, may not receive direct medical benefit from joining.

Why it matters

Potential benefit: Could help clinicians and public-health officials spot early signs of altered brain development and design interventions to protect children exposed to prenatal or early-life risks.

How similar studies have performed: Large cohorts like the ABCD study have shown that multi-site imaging and behavioral data can reveal important developmental patterns, while HBCD is novel in starting in pregnancy and following children through age 10.

Where this research is happening

Blacksburg, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.