Tracking Alzheimer's disease risk and prevention in older adults
Official title: Wisconsin Registry for Alzheimer's Prevention
Funded at University of Wisconsin-Madison · NIH-11055416 · Data updated 2026-11-12
The Wisconsin Registry for Alzheimer’s Prevention (WRAP) is a friendly long-term study for people at risk of Alzheimer's, where you'll help researchers look for early signs of the disease by sharing information about your brain health, lifestyle, and other health conditions as you age.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | June 1, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $5,708,792 |
| NIH project number | 5R01AG027161-14 |
| Project ID | NIH-11055416 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 65 and older, particularly those with a family history of Alzheimer's or other risk factors.
✕Less likely to help
Patients who are younger than 65 or do not have any risk factors for Alzheimer's disease may not benefit from this research.
What this research studies
The Wisconsin Registry for Alzheimer’s Prevention (WRAP) is a long-term study that monitors individuals at risk for Alzheimer's disease from midlife into older age. It aims to identify early signs of Alzheimer's, including changes in brain proteins and cognitive abilities, before symptoms appear. Participants undergo regular assessments of their cognitive function, lifestyle, and health factors to understand how these elements influence the onset of Alzheimer's and related disorders. The study also examines the impact of other health conditions, such as vascular disease, on cognitive decline.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better prevention strategies for Alzheimer's disease, improving outcomes for at-risk individuals.
How similar studies have gone: Previous research has shown promising results in identifying early biomarkers for Alzheimer's disease, indicating that this approach has potential for success.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Johnson, Sterling C — University of Wisconsin-Madison
- Study coordinator: Johnson, Sterling C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.